PAMAM dendrimers in the tanning industry has a wide range of applications: (a) as formaldehyde scavenger. Leather’s tanning, retanning and bleaching processes will produce a large number of formaldehyde,terminal amino PAMAM dendrimers with lots of reactive amino groups , can react with formaldehyde to effectively reduce the formaldehyde content, can be used as a kind of excellent performance formaldehyde scavenger; (2) as a soaking agent. Hydrocarbon chains of PAMAM and methyl group are lipophilic group, carboxyl and amine groups are hydrophilic, it will have more excellent surface active properties. Thus,dendrimer-NH2 end group can be modified according to the actual needs by the introduction of favorable soaking groups for the leather to obtain some effective macromolecular surfactant to reduce the required additives amount of soaking step , so as to achieve the purpose of environmental conservation; (3) as leveling agent and fixative.By appropriate modification of PAMAM, such as using cationic etherification grafts and modifies amino group of entire generation dendrimers PAMAM to bring a large number of peripheral cationic group and form a large number of ionic bonds with anionic dye to form macromolecules lake on the fiber surface, which plays a fixation effect; (4) as tanning agent and chrome tanning agents. Carboxyl-terminated dendrimer product may compound with Cr3 +, chromium salt content in tanning liquid waste can be reduced to decrease chrome pollution of the environment, to achieve clean and less chrome tanning purposes; (5) as flocculant for leather wastewater. As a new type of polymer flocculant, it can combine with the high organic matter, suspended solids, Cr (Ⅲ) and neutral salt which is contained in tanbnery wastewater to form suspended solids settling down. It has good flocculation effect, which is with less dosage,for wide pH range and easy operation, and can be used twice after treatment . Weihai CY Dendrimer Technology Co. Ltd forwards from “PAMAM dendrimer type Compounds and Their Application in the leather industry,” Ma Cha, Long Li, YiLong Li, Zhenglian Pang, Xinbin Yi, Hao Yu, Jiangxi Normal University, Jiangxi Province Key Laboratory of Organic Chemistry Nanchang, Jiangxi 330013 China Petroleum Exploration and Development Research Institute, Beijing 100083 China Leather Vol.53 19 October 2011 Precipitated crystals.